RecruitingPhase 2NCT06062875

Effects of TNF Blockade on Human BPH/LUTS


Sponsor

Endeavor Health

Enrollment

70 participants

Start Date

Jan 24, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Specific Aim 1. To evaluate the efficacy of TNF antagonist action in BPH/LUTS Specific Aim 2. Define the consequences of TNF antagonist therapy on prostate tissue Specific Aim 3. Identify genetic predictors to stratify patients with differential response to TNF-antagonist therapy.


Eligibility

Sex: MALEMin Age: 45 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Adalimumab for people with benign prostatic hyperplasia (bph). The study is currently recruiting participants at 1 location. People eligible for this study include men aged 45 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGAdalimumab

Adalimumab will be delivered subcutaneously (under the skin) at a dose of 40mg every 2 weeks for a total of 6 doses.


Locations(1)

NorthShore University HealthSystem

Glenview, Illinois, United States

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NCT06062875


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