RecruitingNot ApplicableNCT06066606
U-LABA/ICS Effects on Exercise Performance, Vilanterol
Physiological Response to U-LABA/ICS With Emphasis on Exercise Performance, Vilanterol
Sponsor
Morten Hostrup, PhD
Enrollment
30 participants
Start Date
Oct 3, 2023
Study Type
INTERVENTIONAL
Conditions
Summary
The purpose of the project is to investigate exercise performance in humans following bronchodilation induced by acute inhalation of beta2-agonist vilanterol + fluticasone furoate
Eligibility
Min Age: 18 YearsMax Age: 39 Years
Inclusion Criteria3
- Age 18-39
- Physically active > 5 h weekly
- Maximal oxygen consumption classified as high or very high
Exclusion Criteria10
- Diagnosed with severe asthma and been in treatment with long-acting beta2-agonist/corticosteroid
- ECG abnormality
- ACQ score > 1.5
- Severe bronchial hyperreactivity as determined by mannitol test
- FEV1/FVC ratio < 0.7 determined with spirometry
- Chronic illness determined to be a potential risk for participant during study
- In chronic treatment with medication that may interfere with study results
- Pregnancy
- Smoker
- Blood donation during the past 3 months
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Interventions
DRUGVilanterol and Fluticasone Furoate (low dose)
Participants are administered 25 µg of vilanterol + fluticasone furoate
DRUGVilanterol and Fluticasone Furoate (high dose)
Participants are administered 100 µg of vilanterol + fluticasone furoate
DRUGPlacebo
Participants are administered placebo
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06066606
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