RecruitingNCT06068114

Gastric Pathophysiology in Diabetes

Detailed Assessment of Gastric Functions in Patients With Diabetes Mellitus


Sponsor

Institute for Clinical and Experimental Medicine

Enrollment

120 participants

Start Date

Oct 5, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

This is a comprehensive pathophysiological study assessing various gastric functions in patients with diabetes mellitus. The investigators aim to examine the stomach with various measurement devices to gain information about its different functions and malfunctions. After the initial measurements, the examinations will be repeated after a year in each patient. Changes in the measurement values will be examined and their relations to each other and to the overall health of the patients will be investigated. For example it is hypothesised that diabetic patients also suffering from functional dyspepsia or gastroparesis will also show some changes in the function of the pyloric muscle.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study looks at how diabetes affects the stomach's ability to empty food properly (called gastric motility). It uses specialized tests to measure how the stomach moves and processes food, comparing people with diabetes to healthy controls, to better understand digestive complications of the disease. **You may be eligible if...** - You have been diagnosed with type 1 or type 2 diabetes for at least 3 years - You have been on diabetes medication (drugs or insulin) for at least 2 years **You may NOT be eligible if...** - Your type 2 diabetes is managed by diet alone (no medication) - Your diabetes is severely uncontrolled and requires hospitalization - You are taking more than one medication that speeds up stomach emptying (prokinetics) - You are currently on or recently used opioid pain medications - You have had major surgery on the stomach or esophagus Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(5)

Nemocnice AGEL Ostrava-Vítkovice a. s.

Ostrava, Czechia

University Hospital Ostrava

Ostrava, Czechia

Institute for Clinical and Experimental Medicine

Prague, Czechia

Military University Hospital Prague

Prague, Czechia

University Hospital Trnava

Trnava, Slovakia

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NCT06068114


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