RecruitingNCT06071507

Management of Malignant Gastric Outlet Obstruction Between Surgery and Endoscopy

Sponsor

IRCCS San Raffaele

Enrollment

250 participants

Start Date

Apr 15, 2024

Study Type

OBSERVATIONAL

Conditions

Pancreatic Cancer Gastric Outlet Obstruction

Summary

The aim of this observational study is to compare the outcomes of three different procedures performed for the management of malignant Gastric Outlet Obstruction due to Pancreatic Cancer. Patients who undergo: * Surgical gastroenterostomy * Endoscopic placement of a self-expanding metallic stent * EUS-guided gastroenterostomy in accordance with standard clinical practice, will be enrolled to evaluate potential differences between the procedures in terms of clinical success, eating experience, chemotherapy tolerance, and nutritional status during follow-up. Participants will be asked to complete a quality of life questionnaire at baseline and during follow-up; however, no additional procedures will be conducted as a result of participation in the study.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study compares different procedures for relieving a blockage in the stomach outlet caused by pancreatic cancer — a condition called gastric outlet obstruction. Researchers compare endoscopic procedures (using a camera through the mouth) with traditional bypass surgery to find out which approach is safest and most effective. **You may be eligible if...** - You have confirmed pancreatic cancer - Your cancer diagnosis is within the last 6 months and you are eligible for active cancer treatment - You have a blockage in the stomach outlet (gastric outlet obstruction) confirmed by imaging or endoscopy - You are a candidate for one of the procedures being studied - You are 18 or older **You may NOT be eligible if...** - You are under 18 - Your blockage is caused by a non-cancerous condition or a different type of cancer - Your cancer has spread widely and active treatment is no longer being pursued Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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