RecruitingNot ApplicableNCT06074276

The Effects of Almond on Facial Skin Collagen and Wrinkles

Prospective Randomized Controlled Trial on the Effects of Almond on Facial Skin Collagen and Wrinkles


Sponsor

Integrative Skin Science and Research

Enrollment

60 participants

Start Date

Oct 4, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Investigate the effects of almond consumption on collagen production, elastin levels, wrinkles, and pigmentation among premenopausal women and postmenopausal women belonging to all Fitzpatrick skin types.


Eligibility

Sex: FEMALEMin Age: 35 YearsMax Age: 70 Years

Inclusion Criteria6

  • Subjects 35 to 70 years of age of all skin types
  • % of the subjects will be postmenopausal women determined as \>1-year loss of menstrual period
  • % of the subjects will be premenopausal women
  • BMI 18.5 - 35 kg/m2
  • Individuals with a habitual diet that has been maintained for at least 6 months and to be maintained for the duration of the study
  • Individuals must maintain their usual skincare products, defined as products that has been used for at least 1 month, for the duration of the study

Exclusion Criteria9

  • Those with a nut allergy
  • Those who are unwilling to discontinue oral collagen supplementation 1 month prior to the start of the study
  • Individuals who are unwilling to discontinue vitamin E or nut containing supplements 2 weeks prior to and during the intervention.
  • Individuals who are pregnant or breastfeeding
  • Change in skincare products during the study
  • Had a medical or cosmetic procedure such as laser resurfacing or plastic surgery to the face within the last 6 months (include botulinum toxin, dermal fillers, collagen, or other similar cosmetic procedure)
  • Has an autoimmune photosensitive condition or known genetic condition with a deficiency in collagen production (such as Ehler-Danlos)
  • Those with a skin disease on their face that would affect the assessment of their skin based on the assessment of the investigator.
  • Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years

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Interventions

OTHERFood: whole almonds

60 grams or (\~2 oz) will be consumed 5 times per week.

OTHERFood: non-nut snack

Protein and calorie matched non-nut-based food will be consumed 5 times per week by mouth


Locations(1)

Integrative Skin Science and Research

Sacramento, California, United States

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NCT06074276


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