Pigmentation Clinical Trials

2 recruiting

Frequently Asked Questions

Common questions about Pigmentation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 20 trials

Recruiting
Not Applicable

Clinical Effectiveness Of Polishing Brush Compared To Ceramic Soft Tissue Trimming Bur In Gingival Depigmentation

Gingival Hyperpigmentation
Cairo University20 enrolled1 locationNCT07402720
Recruiting

The Impact of Skin Tone on Pulse Oximeter Accuracy

Accuracy of Pulse Oximetry Across Skin Pigmentation Levels
Rush University Medical Center194 enrolled1 locationNCT07415187
Recruiting
Not Applicable

Clinical Evaluation of Microneedling Technique With Topical Application of Silymarin on Gingival Hyperpigmentation in Comparison With Diode Laser and Scalpel Methods.

Gingival PigmentationGingival Hyperpigmentaion
Fayoum University30 enrolled1 locationNCT07410156
Recruiting
Not Applicable

Microneedling With Platelet Rich Plasma Versus Microneedling Alone For Gingival Depigmentation

Gingival Pigmentation
Cairo University32 enrolled3 locationsNCT07359339
Recruiting
Phase 4

Prospective Evaluation of Topical Almond Oil vs Hydroquinone

Skin Pigmentation
University of California, Davis50 enrolled1 locationNCT04875715
Recruiting

Pulse Oximeter Accuracy in Healthy Humans During Hypoxia

HypoxiaSkin Pigmentation
University of California, San Francisco10,000 enrolled1 locationNCT06142019
Recruiting

National Ophthalmic Genotyping and Phenotyping Network (eyeGENE (Registered Trademark)), Stage 3 - Expansion of DNA and Data Repositories for Rare Inherited Ophthalmic Diseases

AniridiaAlbinismCorneal Dystrophy+4 more
National Eye Institute (NEI)1,000 enrolled2 locationsNCT06491615
Recruiting
Not Applicable

The Effectiveness of a Novel Lip Product Containing Caulerpa Lentillifera Extract for Reducing Lip Hyperpigmentation

Hyperpigmentation
Chulalongkorn University30 enrolled1 locationNCT07067879
Recruiting
Not Applicable

Characterization of Bacterial and Mycosis Skin Flora in Seborrheic Macular Hypopigmentation - Microbiome

Hypopigmentation
Centre Hospitalier Universitaire de Nice20 enrolled3 locationsNCT06908889
Recruiting
Phase 1Phase 2

Autologous Adipose Cells Therapy

Hair ThinningHair Loss/BaldnessWrinkle Appearance+5 more
CERM INC.40 enrolled2 locationsNCT06869252
Recruiting
Not Applicable

Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color

HyperpigmentationAcne Scars - Mixed Atrophic and HypertrophicLaser-Induced Hyperpigmentation
Albert Einstein College of Medicine46 enrolled1 locationNCT05362929
Recruiting
Not Applicable

The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles

WrinkleCollagen DegenerationPigmentation+2 more
Integrative Skin Science and Research90 enrolled1 locationNCT06571721
Recruiting
Not Applicable

Efficacy and Tolerability of Tested Formula After 3 Months of Treatment of Facial Hyperpigmentation of 3 Origins

Hyperpigmentation
Cosmetique Active International72 enrolled1 locationNCT06253468
Recruiting
Not Applicable

Efficacy and Tolerability of the Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 Origins

Hyperpigmentation
Cosmetique Active International60 enrolled1 locationNCT06268496
Recruiting
Not Applicable

The Effects of Almond on Facial Skin Collagen and Wrinkles

WrinkleCollagen DegenerationPigmentation+1 more
Integrative Skin Science and Research60 enrolled1 locationNCT06074276
Recruiting

Tattoo Particles: Picosecond Laser Versus Nanosecond Laser

Tattoo; Pigmentation
Universitätsklinikum Hamburg-Eppendorf20 enrolled1 locationNCT06431464
Recruiting
Not Applicable

Pilot Study of LED for PIE and PIH

Hyperpigmentation
Yanjun Dan10 enrolled1 locationNCT06349447
Recruiting
Phase 4

The Adjunctive Role of Vitamin C on Pigment Recurrence (Randomized Clinical and Histological Trial)

Gingival Pigmentation
Ain Shams University24 enrolled1 locationNCT06312605
Recruiting
Not Applicable

Enhancing Children's Cognitive Function and Achievement Through Carotenoid Consumption

Cognitive ChangeAchievementMacular Pigmentation
University of Illinois at Urbana-Champaign288 enrolled1 locationNCT05177679
Recruiting
Not Applicable

Partial Breast Versus no Irradiation for Women With Early Breast Cancer

Local Neoplasm RecurrenceDistantly Metastatic Malignant NeoplasmDeath+6 more
Danish Breast Cancer Cooperative Group926 enrolled17 locationsNCT03646955