RecruitingPhase 1NCT06075810

A Study of Oral MBQ-167 in Participants With Advanced Breast Cancer

A Phase 1 Open-Label, First-in-Human Trial of Oral MBQ-167 as Single Agent in Participants With Advanced Breast Cancer


Sponsor

MBQ Pharma

Enrollment

48 participants

Start Date

Nov 9, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

A Phase 1, open-label, dose-escalation clinical trial of MBQ-167 in participants with advanced Breast Cancer for whom Standard of Care (SOC) has failed or has proven intolerable.


Eligibility

Min Age: 21 Years

Plain Language Summary

Simplified for easier understanding

This study is testing an oral drug called MBQ-167 in people with advanced breast cancer that has already been treated with approved therapies. It is an early-phase study to assess how safe and effective this new drug is. **You may be eligible if...** - You have advanced breast cancer confirmed by tissue or cell testing - Your cancer has continued to grow despite receiving approved treatments - You meet other medical criteria assessed by the study investigator **You may NOT be eligible if...** - Your breast cancer has not been previously treated - You have another serious medical condition that would make participation unsafe - You do not meet additional criteria evaluated by the study team Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGMBQ-167

MBQ-167, an inhibitor of Rho GTPases Rac and Cdc42


Locations(4)

Precision Next Gen Oncology & Research Center

Beverly Hills, California, United States

Florida Cancer Specialists / Sarah Cannon Research Institute / SCRI

Sarasota, Florida, United States

Sarah Cannon Research Institute/SCRI

Nashville, Tennessee, United States

FDI Clinical Research

San Juan, Puerto Rico

View Full Details on ClinicalTrials.gov

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NCT06075810


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