RecruitingNot ApplicableNCT06082531
Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis
Therapeutic Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis and Periarticular Tissue Injury
Sponsor
Xijing Hospital
Enrollment
300 participants
Start Date
Sep 1, 2023
Study Type
INTERVENTIONAL
Conditions
Summary
To evaluate the safety and effectiveness of PRP injection therapy in the repair of osteoarthritis and periarticular soft tissue injury through a single-center, exploratory clinical study, and to provide a more reliable basis for the treatment of joint injury.
Eligibility
Min Age: 20 YearsMax Age: 60 Years
Inclusion Criteria3
- The age range of the participants was 20 to 60 years old. Through a comprehensive clinical and imaging examination, it was conclusively determined that the individuals had knee osteoarthritis or experienced injuries to the cart, and meniscus surrounding the knee joint.
- The preoperative routine tests and examinations revealed no contraindications.
- Revised sentence: "Informed consent of the patient
Exclusion Criteria8
- The platelet count or function exhibits significant abnormalities、Systemic infection transmitted through the bloodstream.
- Prolonged usage of anti-inflammatory drugs and systemic corticoid administration.
- In injection site or damage to the skin.
- Patients with tumors or undergoing radiotherapy and chemotherapy.
- Pregnant or breastfeeding women.
- Individuals with mental illnesses who are unable to cooperate with follow-up procedures.
- Contraindications for MRI、Patients or their families do consent to participate in the study.
- Other circumstances that render participation in the study unsuitable.
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Interventions
DRUGSodium hyaluronate injection
The control group was injected into the joint cavity with sodium hyaluronate injection..
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06082531
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