RecruitingNot ApplicableNCT06089473

Virtual Home-based Physical Pre-habilitation in Kidney Transplant Candidates

Virtual Home-based Physical Pre-habilitation in Kidney Transplant Candidates: a Pilot RCT

Sponsor

McGill University Health Centre/Research Institute of the McGill University Health Centre

Enrollment

30 participants

Start Date

Nov 2, 2024

Study Type

INTERVENTIONAL

Conditions

Frailty Transplant;Failure,Kidney Kidney Disease, End-Stage

Summary

The goal of this RCT is to address the feasibility of conducting a 12-week virtual pre-habilitation intervention, which includes exercise and education, in kidney transplant candidates. The intervention also includes a 5-month maintenance phase with independent home exercises (maximum of 8 months of intervention/ended early if the participant undergoes a kidney transplant). The main questions it aims to answer are: * estimate the proportion of screened patients who meet eligibility criteria * estimate the proportion of eligible patients who consent to randomization * estimate the proportion of patients who adhere to the interventions * estimate follow-up completion rates * inform the calculation of sample size requirements for a full-scale RCT * assess the acceptability of the intervention by the participants. Participants in the control group will receive usual outpatient care.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a virtual, home-based exercise program before kidney transplant surgery can improve the physical fitness and strength of patients who are frail or pre-frail. Better physical condition before surgery (called 'prehabilitation') may lead to faster recovery and better outcomes after transplant. **You may be eligible if...** - You are 18 or older with end-stage kidney disease (kidney failure) - You are on the waiting list for a kidney transplant (or in the process of being listed) at one of the participating Canadian hospitals - You are classified as frail or pre-frail on a standard frailty test - This is your first or a repeat transplant - You can speak English or French - You can participate in online video calls (or have a household member who can help you connect) **You may NOT be eligible if...** - You are classified as physically robust (no frailty) - You are already participating in a structured exercise program - You have serious health conditions that prevent exercise Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERIntervention Group: Exercise and education.

* Exercise Intervention: 12-weeks of supervised, individualized virtual exercise sessions, delivered by an accredited kinesiologist. Independent unsupervised sessions start at week 5. After 12 weeks, a 5-month maintenance phase is followed, continuing to exercise three times weekly for 30 minutes per session. * Education: Prior to each zoom session with the kinesiologist (starting on week 2), participants will watch short educational videos. Additionally, participants will be provided a document (PDF) of evidence-based strategies to help cope with stress.

OTHERUsual Care Only

Usual Care for kidney transplant candidates, which may include medical visits, nutrition, and psychological support.