RecruitingNCT06092125

Clinical Applicantion of Multi-Tracer PET/MR Imaging in Neurological Disorders/Disease

Sponsor

Xuanwu Hospital, Beijing

Enrollment

2,300 participants

Start Date

Oct 1, 2022

Study Type

OBSERVATIONAL

Conditions

Epilepsy Alzheimer Disease Parkinson Disease Malignant Brain Tumor

Summary

The goal of this clinical trial is to learn about the application of domestic PET/MR in major brain diseases. The main questions it aims to answer are: * Overcome the bottleneck of early accurate diagnosis and treatment in major brain diseases clinical practice. * Promote the clinical application of domestic PET/MR, enhance international competitiveness. Participants will have a PET/MR scan of the brain.

Eligibility

Min Age: 18 YearsMax Age: 60 Years

Inclusion Criteria2

Patients diagnosed with mild cognitive impairment (MCI) or Alzheimer's disease (AD), rapid eye movement sleep behavior disorder (RBD) or Parkinson's disease (PD), epilepsy, malignant brain tumors based on clinical guidelines.
Patients admitted to our hospital for inpatient treatment.

Exclusion Criteria5

Patients who have undergone non-invasive/minimally invasive treatments such as radiotherapy or chemotherapy within the past three weeks. And Patients who have taken Alzheimer's disease-related and Parkinson's disease-related treatment drugs within the past month.
Patients with persistent seizures or status epilepticus that cannot be controlled by medication, resulting in an inability to cooperate with the examination.
patients with poorly controlled blood sugar and ineffective medication intervention.
Patients with absolute contraindications for PET/MR examination.
Karnofsky Performance Score (KPS) \<60.