RecruitingNot ApplicableNCT06092411

Effects of CBT and BLT in Youth With Unipolar Depression and Evening Chronotype

Effects of Cognitive Behavioural Therapy and Bright Light Therapy in Youth With Unipolar Depression and Evening Chronotype: An Assessor-blind Parallel-group Randomised Controlled Trial

Sponsor

The University of Hong Kong

Enrollment

162 participants

Start Date

Oct 31, 2023

Study Type

INTERVENTIONAL

Conditions

Depression, Unipolar Eveningness

Summary

The goal of this prospective randomised controlled trial is to examine the effects of cognitive behavioural therapy and bright light therapy in youths with unipolar depression and evening chronotype. The main questions it aims to answer are: 1. What is the efficacy of CBT-D and CBT-D plus bright light therapy in reducing depression severity in adolescents with depression and eveningness? 2. What are the effects of CBT-D and CBT-D plus bright light therapy on the subjective and objective sleep and circadian measures, as well as the quality of life, daytime symptoms, and functioning (e.g., sleepiness, fatigue)? Participants will participate in 8 weekly group sessions of CBT-D intervention based on the well-established CBT elements for treating depression. Concurrently participants will also be asked to wear a portable light device at home for 30 minutes daily for seven weeks, starting from the second week of the group intervention. Participants in the CBT-D only group will receive a placebo light via the device, whereas participants in the CBT-D plus light therapy group will receive the active bright light via the device.

Eligibility

Min Age: 12 YearsMax Age: 20 Years

Plain Language Summary

Simplified for easier understanding

This study is testing two non-medication treatments for depression in young people who tend to stay up late (evening chronotype): cognitive behavioral therapy (CBT, a type of talk therapy) and bright light therapy (using a special lamp). Researchers want to see if these approaches can ease depression symptoms in teens and young adults who are also night owls. **You may be eligible if...** - You are Chinese and aged 12–20 years old - You have been diagnosed with a depressive disorder - Your depression symptoms are at a moderate or higher level on a rating scale - You typically fall asleep late (11:15 PM or later depending on your age) at least 3 nights per week - A parent or guardian can provide consent if you are under 18 **You may NOT be eligible if...** - You currently use substances or have a history of manic or psychotic episodes - You have a diagnosis of bipolar disorder - You have a serious physical illness or are pregnant - You require urgent psychiatric care Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALCognitive Behavioural Therapy for Depression

Consists of 8 weekly sessions (group-based, 90-min, 4-6 adolescents in each group). The intervention focuses on addressing depression, with the components such as psycho-education on depression, self-monitoring, behavioural activation, and cognitive restructuring (addressing negative and irrational thoughts often associated with depression in adolescents), relaxation techniques, and relapse prevention.

DEVICEBright Light Therapy

Participants will undergo daily morning light therapy by wearing a validated portable light emitting device (i.e., Re-Timers: https://www.re-timer.com/) at home for 30 minutes. Participants will receive bright blue-green light (500 nm, 506 lux).

Locations(1)

Sleep Research Clinic & Laboratory, Department of Psychology, The University of Hong Kong

Hong Kong, Hong Kong

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NCT06092411

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