COGNIFOOD-Changing the Carbohydrate/Fat-ratio to Prevent Cognitive Decline and Alzheimer Pathology: A Pilot Study

The COGNIFOOD study is a pilot trial testing whether changing the ratio of carbohydrates to fats in the diet can slow cognitive decline and reduce Alzheimer's-related brain changes in people with very early (prodromal) Alzheimer's disease — meaning they have mild memory and thinking difficulties with biological evidence of Alzheimer's pathology. **You may be eligible if...** - You have been diagnosed with mild cognitive impairment due to Alzheimer's disease, with biological confirmation (via spinal fluid, MRI, or PET scan) - You score 20 or higher on a standard cognitive test (MoCA) - You have a willing and available study partner who can support you and report on your progress - You are motivated to prepare most of your meals according to study guidelines - You can eat plant-based food plus at least one of: fish, meat, or eggs/dairy - You can complete cognitive tests in Swedish **You may NOT be eligible if...** - You have full dementia (not just mild impairment) - You have diabetes, familial hypercholesterolemia, or uncontrolled high blood pressure - Your BMI is below 18 or above 35 - You are currently on metformin, GLP-1 medications, or SGLT-2 inhibitors - You have alcohol or substance use problems Talk to your doctor to see if this trial is right for you.