Low-dose Versus Standard-dose Rivaroxaban in Elderly Patients With Atrial Fibrillation
The Efficacy and Safety of Low-dose Versus Standard-dose Rivaroxaban in Elderly Patients With Atrial Fibrillation
China National Center for Cardiovascular Diseases
4,374 participants
Sep 1, 2024
INTERVENTIONAL
Conditions
Summary
To evaluate the efficacy and safety of low-dose versus standard-dose rivaroxaban anticoagulation therapy in elderly patients with atrial fibrillation.
Eligibility
Plain Language Summary
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Interventions
Rivaroxaban 15mg q.d. (The dose should be reduced to 10mg q.d. in the following special populations: 1. Creatinine clearance \<50 mL/min; 2. Body weight ≤60kg; 3. Age ≥80 years old)
Rivaroxaban 20mg q.d. (The dose should be reduced to 15mg q.d. in the following special populations: 1. Creatinine clearance \<50 mL/min; 2. Body weight ≤60kg; 3. Age ≥80 years old)
Locations(1)
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NCT06108414