RecruitingNCT06114784
Microbiome and Host Susceptibility in Severe Pneumonia, a Prospective, Multicenter, Cohort Study
Identification of Lung and Intestinal Microbiome and Host Susceptibility in Severe Pneumonia, a Prospective, Multicenter Cohort Study
Sponsor
First Affiliated Hospital of Zhejiang University
Enrollment
2,000 participants
Start Date
Sep 25, 2023
Study Type
OBSERVATIONAL
Conditions
Summary
This study was a prospective multicenter cohort of severe pneumonia. And by collecting clinical samples to clarify the correlation between lung microbiome, intestinal microbiome, host susceptibility, and prognosis of severe pneumonia patients.
Eligibility
Min Age: 18 Years
Inclusion Criteria1
- \. New lung infection that meets one of the following definitions: the patient receives mechanical ventilation (invasive or non-invasive) due to acute respiratory failure, with a PEEP level of 5cm or above; Patients receiving high flow oxygen therapy with a FiO2 of 50% or more and a PaO2: FiO2 ratio below 300
Exclusion Criteria2
- Expected length of stay in ICU is less than 1 day
- Pregnant
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
DIAGNOSTIC_TESTMetagenomics
Clinical metagenomics is used to evaluate pathogens
Locations(15)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06114784