RecruitingNot ApplicableNCT06115395

Non-invasive Ventilation Assisted Fiber-optic Bronchoscopy

Efficacy and Safety of Using Non-invasive Ventilation Assisted Fiber-optic Bronchoscopy


Sponsor

Mansoura University

Enrollment

100 participants

Start Date

Jul 25, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is the evaluation of using bi-level positive airway pressure ventilation in candidates for fiber-optic bronchoscopy regarding benefits and drawbacks.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria3

  • Patients who admitted to the pulmonology ward or intensive care unit with any (diagnostic and/or therapeutic) bronchoscopy indication.
  • Age 18 years or more.
  • Patients accepted to participate in the study.

Exclusion Criteria11

  • Patients with:
  • Cardiac or respiratory arrest.
  • Impaired consciousness or confusion.
  • Type II respiratory failure.
  • Hemodynamic instability.
  • Inability to cooperate or to protect the airway.
  • Vomiting, bowel obstruction, recent upper gastrointestinal tract surgery and esophageal injury.
  • Patients refusing participation in the study.
  • Patients unfit for NIV and or NIV mask.
  • Intubation and or invasive ventilation candidates.
  • Presence of contraindications for bronchoscopy procedure such as insufficient platelet number or coagulopathy.

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Interventions

DEVICEnon- invasive ventilator

Group 1 (hypoexemic patient who will undergo bronchoscopy under non- invasive ventilation{NIV} and conventional o2 therapy) will be on NIV half an hour prior and throughout the bronchoscopic sampling and after the procedure until reach the baseline criteria

DEVICEfiber-optic bronchoscopy

Group 2 (hypoxemic patients who will undergo conventional bronchoscopy under conventional o2 therapy without NIV ) will be on conventional oxygen therapy half an hour prior and throughout the bronchoscopic sampling and after the procedure until reach the baseline criteria

DEVICEnon- invasive ventilator

Group 3 (non- hypoxemic patients who will undergo bronchoscopy under non- invasive ventilation{NIV} and conventional o2 therapy) will be on NIV throughout the bronchoscopic sampling and after the procedure until reach the baseline criteria

DEVICEfiber-optic bronchoscopy

Group 4 (non- hypoxemic patients who will undergo conventional bronchoscopy without non- invasive ventilation{NIV) will be on conventional oxygen therapy throughout the bronchoscopic sampling and after the procedure until reach the baseline criteria


Locations(1)

Walaa Maher Abd ElAziz,

Al Mansurah, Egypt

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NCT06115395


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