Diseases Clinical Trials

2,077 recruitingLast updated: July 25, 2026

There are 2,077 actively recruiting diseases clinical trials across 110 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 4, Phase 3, Early Phase 1. Top locations include Boston, Massachusetts, United States, New York, New York, United States, London, United Kingdom. Updated daily from ClinicalTrials.gov.


Diseases Trials at a Glance

2,077 actively recruiting trials for diseases are listed on ClinicalTrialsFinder across 6 cities in 110 countries. The largest study group is Not Applicable with 785 trials, with the heaviest enrollment activity in Boston, New York, and London. Lead sponsors running diseases studies include Assistance Publique - Hôpitaux de Paris, Chinese University of Hong Kong, and Fondazione Policlinico Universitario Agostino Gemelli IRCCS.

Treatments under study

About Diseases Clinical Trials

Looking for clinical trials for Diseases? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Diseases trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Diseases clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 2,077 trials

Recruiting

Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke

StrokeBrain DiseaseVascular Diseases+1 more
National Institute of Neurological Disorders and Stroke (NINDS)450 enrolled1 locationNCT06615973
Recruiting

Longitudinal Studies of Patient With FPDMM

Rare DiseasesInherited Hematological DiseasesFPDMM
National Human Genome Research Institute (NHGRI)1,000 enrolled1 locationNCT03854318
Recruiting

Deciphering the Genetic Architecture of Autoimmune Diseases

Autoimmune Diseases
National Human Genome Research Institute (NHGRI)300 enrolled2 locationsNCT06948110
Recruiting
Not Applicable

Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery Lesions

Arterial Occlusive DiseasesPainCardiovascular Diseases+12 more
Teleflex1,859 enrolled2 locationsNCT07258290
Recruiting

Real-life Registry in Patients With Coronary Artery Disease Treated With the SELUTION Sirolimus-eluting Balloon. Selution Iberia Registry

Cardiovascular Diseases
Fundación EPIC960 enrolled11 locationsNCT07256249
Recruiting
Phase 3

Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT Imaging

allogeneic stem cell transplantationCardiovascular DiseasesAcute Lung Injury+3 more
National Heart, Lung, and Blood Institute (NHLBI)210 enrolled1 locationNCT07613099
Recruiting

Natural History of Stroke: Cause and Development

Brain DiseaseVascular DiseasesIschemic Attack, Transient+2 more
National Institute of Neurological Disorders and Stroke (NINDS)4,000 enrolled3 locationsNCT00009243
Recruiting

Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics

Genetic diseasesFeverROSAH+4 more
National Human Genome Research Institute (NHGRI)5,000 enrolled5 locationsNCT00001373
Recruiting
Not Applicable

NAVIGATE Kidney: A Multi-level Intervention to Reduce Kidney Health Disparities

Chronic Kidney DiseasesKidney Diseases
University of Colorado, Denver448 enrolled2 locationsNCT06810622
Recruiting
Not Applicable

Enhancing Physical Function in Older Adults With Chronic Kidney Disease

Chronic Kidney Diseases
Wake Forest University Health Sciences30 enrolled1 locationNCT06738394
Recruiting
Phase 1

Diagnosis of Pheochromocytoma

PheochromocytomaEndocrine DiseaseEndocrine Diseases
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)3,000 enrolled1 locationNCT00004847
Recruiting

Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in People Living With and Without HIV

ImmunodeficienciesHIVInfectious Diseases
National Institute of Allergy and Infectious Diseases (NIAID)2,419 enrolled2 locationsNCT00001281
Recruiting
Phase 2

A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)

ObesityBody WeightOverweight+5 more
Pfizer872 enrolled65 locationsNCT07575932
Recruiting
Phase 2

Bioenergetic Effect of Pioglitazone in CLD-PH

Pulmonary HypertensionPulmonary Hypertension Due to Lung Diseases
Emory University20 enrolled1 locationNCT06336798
Recruiting
Not Applicable

Virtual Reality (VR) -Directed Brain Gut Behavioral Treatment (BGBT) for Inflammatory Bowel Disease (IBD) Inpatients

Inflammatory Bowel Diseases
University of Michigan40 enrolled1 locationNCT06188793
Recruiting
Not Applicable

Developing a Self-Management Intervention to Improve Health Outcomes for Patients With Inflammatory Bowel Disease

Inflammatory Bowel DiseasesCrohn DiseaseUlcerative Colitis
University of Michigan40 enrolled1 locationNCT07456566
Recruiting
Phase 3

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Colorectal NeoplasmsNeoplasms by SiteGastrointestinal Neoplasms+7 more
Pfizer800 enrolled285 locationsNCT07222800
Recruiting
Not Applicable

The TRICURE EFS Study

Cardiovascular DiseasesTricuspid Valve RegurgitationHeart Valve Diseases
TRiCares15 enrolled10 locationsNCT06506942
Recruiting
Phase 2

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

Central Nervous System DiseasesBrain CancerGlioblastoma Multiforme (GBM)+4 more
Black Diamond Therapeutics, Inc.162 enrolled22 locationsNCT07326566
Recruiting
Not Applicable

Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care

Cardiovascular DiseasesDepression
VA Office of Research and Development132 enrolled1 locationNCT04877197