Diseases Clinical Trials

1,978 recruitingLast updated: May 13, 2026

There are 1,978 actively recruiting diseases clinical trials across 109 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 4, Phase 3, Early Phase 1. Top locations include Boston, Massachusetts, United States, New York, New York, United States, London, United Kingdom. Updated daily from ClinicalTrials.gov.


Diseases Trials at a Glance

1,978 actively recruiting trials for diseases are listed on ClinicalTrialsFinder across 6 cities in 109 countries. The largest study group is Not Applicable with 741 trials, with the heaviest enrollment activity in Boston, New York, and London. Lead sponsors running diseases studies include Assistance Publique - Hôpitaux de Paris, Chinese University of Hong Kong, and Fondazione Policlinico Universitario Agostino Gemelli IRCCS.

Treatments under study

About Diseases Clinical Trials

Looking for clinical trials for Diseases? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Diseases trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Diseases clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 1,978 trials

Recruiting

Deciphering the Genetic Architecture of Autoimmune Diseases

Autoimmune Diseases
National Human Genome Research Institute (NHGRI)300 enrolled2 locationsNCT06948110
Recruiting

Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke

StrokeBrain DiseaseVascular Diseases+1 more
National Institute of Neurological Disorders and Stroke (NINDS)450 enrolled1 locationNCT06615973
Recruiting

Natural History Study of Parathyroid Disorders

Multiple Endocrine Neoplasia Type 1Primary HyperparathyroidismParathyroid Cancer+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)3,000 enrolled1 locationNCT04969926
Recruiting

Diabetes and Heart Disease Risk in Blacks

ObesityCardiovascular DiseasesHypertension+1 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,000 enrolled1 locationNCT00001853
Recruiting

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks

HypertensionCardiovascular DiseaseAdrenal Gland Neoplasm+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1,150 enrolled1 locationNCT03374215
Recruiting

Evaluation of Adults With Endocrine and Metabolic-Related Conditions

Endocrine Diseases
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1,250 enrolled1 locationNCT02830308
Recruiting
Phase 1Phase 2

Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection

Prostate CancerMetastatic Castration-resistant Prostate CancerUrogenital Neoplasms+3 more
Blue Earth Therapeutics Ltd82 enrolled21 locationsNCT05413850
Recruiting
Phase 2

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

Central Nervous System DiseasesBrain CancerGlioblastoma Multiforme (GBM)+4 more
Black Diamond Therapeutics, Inc.162 enrolled5 locationsNCT07326566
Recruiting
Phase 3

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

CardiomyopathiesAmyloidosisHeart Diseases+3 more
Eidos Therapeutics, a BridgeBio company587 enrolled101 locationsNCT06563895
Recruiting

Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in People Living With and Without HIV

ImmunodeficienciesHIVInfectious Diseases
National Institute of Allergy and Infectious Diseases (NIAID)2,419 enrolled2 locationsNCT00001281
Recruiting

AI Assisted Screening for VHD Using Routine Chest CT Scans

Heart Valve Diseases
Second Affiliated Hospital, School of Medicine, Zhejiang University3,000 enrolled3 locationsNCT07449130
Recruiting
Phase 1

Clinical Trial of TQH3906 Capsules for the Treatment of Adult Patients With Moderately to Severely Active Ulcerative Colitis or Crohn's Disease

Inflammatory Bowel Diseases
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.135 enrolled30 locationsNCT06754891
Recruiting

A Database Study of Disease, Treatment Patterns and Healthcare Use in Children With Inflammatory Bowel Diseases in Korea

Inflammatory Bowel Diseases
Janssen Korea, Ltd., Korea8,000 enrolled1 locationNCT07520747
Recruiting

Global Cardio Oncology Registry

Breast CancerCardiotoxicityCardiovascular Diseases+2 more
The Cleveland Clinic5,000 enrolled1 locationNCT05598879
Recruiting
Not Applicable

Infusion of Cell Populations From Unlicensed Umbilical Cord Blood Units

Hematopoietic MalignancyLymphatic Diseases
Masonic Cancer Center, University of Minnesota250 enrolled1 locationNCT01451502
Recruiting

Genetic Analysis of Uncommon Disease Presentations in Non-US Populations

Rare DiseasesUndiagnosed Diseases
National Human Genome Research Institute (NHGRI)400 enrolled1 locationNCT06595940
Recruiting

Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia

Dental Diseases
University Hospital, Toulouse120 enrolled9 locationsNCT06506734
Recruiting

Aging, Geriatric Syndromes and Clonal Hematopoiesis

Geriatric syndromesCardiovascular DiseasesAged+1 more
Washington University School of Medicine2,000 enrolled1 locationNCT02604563
Recruiting
Not Applicable

Artificial Intelligence Delivered Cardiac Magnetic Resonance - Prospective Validation

Cardiovascular DiseasesHealthy Volunteers
Imperial College London150 enrolled1 locationNCT06061822
Recruiting
Phase 1

Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Leukoencephalopathy

Multiple SclerosisProgressive Multifocal LeukoencephalopathyOther Neuroinflammatory Diseases With BBB Leakage
National Institute of Neurological Disorders and Stroke (NINDS)15 enrolled1 locationNCT05849467