RecruitingNot ApplicableNCT06118502

A Clinical Trial of Adaptive Treatment for Early Smoking Cessation Relapse


Sponsor

Medical University of South Carolina

Enrollment

544 participants

Start Date

Mar 25, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This is a research study to find out if treatment decision making can be improved for smokers who find it difficult to quit with medications. Everyone who participates in this study will receive free product, either nicotine replacement therapies (patches and lozenges), varenicline, or a harm reduction product (e-cigarette) for a full 12 weeks. Most participants will receive some combination of these treatments, depending on individual response to each. All visits and study assessments will be entirely remote. All treatments will be provided free of charge for the first 12 weeks. After that, the study team will contact the participants 6 months after the first study phone call to complete another survey. The study lasts six months and will involve 8 surveys.


Eligibility

Min Age: 21 Years

Inclusion Criteria1

  • Smokers who want to quit

Exclusion Criteria1

  • Non-smokers

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Interventions

BEHAVIORALSwitching to a different medication

Participants will receive four weeks of the other FDA approved option, either varenicline or combination NRT, with instructions to try to quit again at week 4.

BEHAVIORALContinued use of the same medication

Participants will receive four additional weeks of the same medication (varenicline or NRT) with instructions to try to quit again at week 4.

BEHAVIORALSwitching to a harm reduction tobacco product

Participants will receive four weeks of e-cigarette products with instructions to switch completely at Week 8


Locations(1)

Medical University of South Carolina

Charleston, South Carolina, United States

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NCT06118502


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