Cardiovascular Effects of a Healthy Dietary Pattern Containing Eggs

This study is testing whether eating 2 eggs per day as part of a healthy diet has different effects on heart health compared to a healthy diet that includes only 3 eggs per week, over a 4-week period. Researchers will measure blood markers of cardiovascular health and function to see whether higher egg intake raises or does not raise the risk of heart disease in the context of an otherwise healthy eating pattern. Adults with moderately elevated LDL cholesterol (115–190 mg/dL), a BMI of 25–35, and normal blood pressure and blood sugar who eat fewer than 14 eggs per week are eligible — those with diabetes, heart disease, liver or kidney disease, or who follow a vegetarian diet are not. Participation involves following a provided meal plan for two 4-week dietary periods (with a washout break in between), attending study visits for blood draws, and avoiding certain supplements and alcohol during the trial. This summary was prepared with AI assistance to help patients understand the study in plain language.