Application of Early Bundle Management of Mechanical Ventilation to Prevent Ventilator Dependence in Children
Children's Hospital of Fudan University
150 participants
Sep 1, 2024
INTERVENTIONAL
Conditions
Summary
This study is based on the risk factors of previous studies to formulate a bundle treatment plan to prevent ventilator dependence in children, in order to reduce the proportion of ventilator dependence in children and provide a theoretical basis for reasonable intervention of children with mechanical ventilation. Participants will receive intensive rehabilitation, nutrition, and tracheotomy at different time periods. Researchers will compare the control group to see whether it can reduce the incidence of ventilator dependence
Eligibility
Inclusion Criteria2
- （1）All stable children receiving mechanical ventilation
- （1）Stable condition: respiratory rate does not exceed 20% of the basic respiratory rate, PEEP< 8. 60%, VIS score< 20, there is no hypotension (70mmHg+ age ×2, 70mmHg under one year old), no higher than the P95 of the same sex and age
Exclusion Criteria9
- Status epilepticus
- Active intracranial hemorrhage
- Intracranial hypertension
- Unstable fracture of the spine
- Spinal cord injury
- There are injuries that affect the implementation of rehabilitation
- Acute surgery was performed on the same day.
- Body temperature over 40℃
- Brain function failure
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
① electrical diaphragm stimulation, ② electrical muscle stimulation, ③ passive limb movement, ④ respiratory rehabilitation.
(1) nutrition department consultation, (2) MDT to develop individualized nutritional pathways, nutrient formulations and use methods, and achieve the target nutritional level within 2 weeks
early tracheotomy for special diseases (e.g central nervous system diseases) receiving mechanical ventilation 14-21 days recommended tracheotomy
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06125210