RecruitingNCT06125392

Multicenter Registry on Microvascular Dysfunction - Searching a New Ach Spasm Definition

A Multicenter RegIstry on the Diagnosis of Patients with Chronic Angina and No Angiographic CoRonary Artery Stenosis (international Retrospective Collection of Anonymized Patient Data) - Searching a New Ach Spasm Definition


Sponsor

Johannes Gutenberg University Mainz

Enrollment

1,000 participants

Start Date

Sep 30, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The MICRO-SNAPE registry will collect data from patients undergoing investigation of microvascular dysfunction and coronary spasm in Europe and North America.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Inclusion Criteria1

  • Patients who underwent combined measurements of coronary pressure and flow in at least 1 native coronary artery in response to endothelium dependent and independent vasodilators.

Exclusion Criteria2

  • Hemodynamic instability
  • Age <18 years

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Interventions

DIAGNOSTIC_TESTCoronary physiology assessment

Resting distal coronary to aortic pressure ratio, resting flow ratio, fractional flow reserve, Coronary Flow Reserve and Microvascular resistance using the thermodilution method and papaverin or adenosine, Resting distal coronary to aortic pressure ratio, resting flow ratio, fractional flow reserve, Coronary Flow Reserve and Microvascular resistance using the thermodilution method and acetylcholine.


Locations(1)

Center of Cardiology, Cardiology I, university hospital Mainz

Mainz, Rhineland-Palatinate, Germany

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NCT06125392


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