RecruitingNCT05841199

Coronary Flow During Rapid Heart Rates

Coronary Epicardial and Microcirculatory Determinants of Ventricular Tachycardia Tolerability

Sponsor

Imperial College London

Enrollment

70 participants

Start Date

Aug 1, 2023

Study Type

OBSERVATIONAL

Conditions

Coronary microvascular disease Heart Failure Coronary Artery Disease Ventricular Tachycardia Coronary Microvascular Dysfunction

Summary

The goal of this observational study is to learn about the factors which determine how well ventricular tachycardia (VT) is tolerated. The main questions it aims to answer are: 1. What impact does coronary artery disease have on the ability for a patient to tolerate VT? 2. Does treatment of coronary artery disease with stents improve the tolerability of VT? Participants who are undergoing a clinically indicated coronary angiogram or coronary angioplasty procedure will have measurements of blood pressure, coronary pressure and coronary flow made during pacing at a range of heart rates.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Pressure and flow measurement during simulated VT for people with coronary artery disease, coronary microvascular dysfunction, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTPressure and flow measurement during simulated VT

Participants undergoing coronary angiography will have measurements of blood pressure, coronary pressure and coronary flow during simulated VT. VT will be simulated using pacing at a range of heart rates.