Neuromodulation in Patients With Neuropathic Pain and Depression.

This trial is studying whether repetitive transcranial magnetic stimulation (rTMS) — a non-invasive brain stimulation technique — can help reduce both neuropathic pain (nerve pain) and depression at the same time in patients who have both conditions simultaneously. **You may be eligible if:** - You have chronic neuropathic pain (central or peripheral nerve pain present for more than 6 months), rated at least 4 out of 10 in intensity - Your pain occurs at least 4 days a week and has not been fully relieved by recommended medications - Your pain medications have been stable for at least one month - You have been diagnosed with a current depressive episode - Your neurologist has recommended motor cortex rTMS - You are covered by social security **You may NOT be eligible if:** - You have a contraindication to rTMS or MRI (e.g., a pacemaker, epilepsy, metal clips in the brain, certain implants, or claustrophobia) - Your neuropathic pain is from a progressive disease (HIV, cancer, or systemic illness) - You abuse drugs or psychoactive substances - You are under 18 or cannot understand informed consent - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.