RecruitingNot ApplicableNCT06129942

Light Therapy in Parkinson's Disease

Light Therapy in Parkinson's Disease: a Prospective, Observational Study

Sponsor

Second Affiliated Hospital of Soochow University

Enrollment

50 participants

Start Date

Sep 1, 2021

Study Type

INTERVENTIONAL

Conditions

Parkinson Disease Sleep Disorder Circadian Rhythm Disorders

Summary

The aim of this randomized controlled trial (RCT) is to clarify the effect of bright light therapy on motor symptoms and sleep disorders in patients with Parkinson's disease.

Eligibility

Min Age: 50 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying whether light therapy (exposure to a specific type of bright light) can improve sleep quality and other non-motor symptoms in people with Parkinson's disease, as disrupted sleep is a very common and debilitating problem for these patients. **You may be eligible if:** - You have been diagnosed with Parkinson's disease (Hoehn and Yahr stages 2–3, meaning moderate disease affecting both sides of the body) - Your medications have been stable for at least one month - You agree to keep your medications stable throughout the trial **You may NOT be eligible if:** - You take sleeping pills or stimulant drugs - You take antidepressants, unless they have been at a stable dose for more than 3 months - You have significant vision problems (cataracts, glaucoma, or blindness) - You have cognitive impairment (MMSE score below 24) - You have uncontrollable hallucinations or psychiatric symptoms - You work night shifts, have jet lag issues, or have significant circadian rhythm disorders Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEBright light box

The light box uses a spectrally transparent prism diffuser, which can block ultraviolet rays, but will not affect the quality of the filtered light and will not turn yellow. The distance between the light box and the patient should not exceed 65cm.PD patients are selected for light intervention of different intensities. The experimental group is treated with 10,000 Lux intensity. The treatment time is 1 hour each day from 08:00-11:00 in the morning and 17:00-19:00 in the afternoon lasting for a month. The patient is asked to move under the light source, but should not fall asleep.

DEVICEDim Light box

The light box uses a spectrally transparent prism diffuser, which can block ultraviolet rays, but will not affect the quality of the filtered light and will not turn yellow. The distance between the light box and the patient should not exceed 65cm.PD patients are selected for light intervention of different intensities. The control group is treated with 300 Lux intensity. The treatment time is 1 hour each day from 08:00-11:00 in the morning and 17:00-19:00 in the afternoon lasting for a month. The patient is asked to move under the light source, but should not fall asleep.