Protocol CAUSE-03 / CHEETAH

This study (CAUSE-03/CHEETAH) examines asthma management in children and adults living in specific neighborhoods (selected census tracts) and tests whether a structured asthma care program improves outcomes compared to standard care. It also recruits people without asthma for comparison. The study aims to reduce asthma-related disparities in communities with higher pollution or poverty. **You may be eligible if...** - You live in one of the designated neighborhoods or within the metropolitan area with public health insurance - You have a confirmed asthma diagnosis for more than 1 year (or respiratory symptoms for more than 1 year) - You require at least a basic level of asthma treatment (Step 2 or above) - Or, you have never been diagnosed with asthma and haven't used asthma medication in the past year (for the comparison group) - You are able to do breathing tests (spirometry) **You may NOT be eligible if...** - You are currently pregnant or breastfeeding - You have another significant lung disease - You are currently receiving immunotherapy or biologic asthma medications - You have had a life-threatening asthma attack requiring a breathing machine in the past 2 years - You have a known immune deficiency Talk to your doctor to see if this trial is right for you.