RecruitingNot ApplicableNCT06141239

2D/3D Imaging to Analyze the Regeneration Rate of Autologous Bone

Using 2D/3D Imaging to Analyze the Regeneration Rate of Autologous Bone During Alveolar Bone Preservation Surgery Using Periodontal Valves to Completely Cover Autologous Tooth Roots, Bone Substitutes, and Vitamin D3 Treatment

Sponsor

Chang Gung Memorial Hospital

Enrollment

48 participants

Start Date

Jun 6, 2024

Study Type

INTERVENTIONAL

Conditions

Alveolar Ridge Preservation

Summary

Place a collagen plug (collagen plug) in the lower 2/3 to 1/2 of your tooth extraction site while giving you Vit. The extracted teeth are made into autogenous tooth root thin slices and covered in your tooth extraction cavity, and the skin flap raised by your flap surgery is used to cover the autologous tooth root cover to help the autologous tooth roots stabilize and heal the wound, which is different from traditional surgery. The difference in treatment lies in the local use of autogenous tooth root thin slices and Vit.D3. Collagen plug and Vit.D3 are already qualified medical materials and drugs on the market. However, there is no precedent for making thin autologous tooth root slices. will be a trial of a new medical technology that has not yet been used

Eligibility

Min Age: 20 YearsMax Age: 70 Years

Inclusion Criteria4

Willing to sign written subject consent
The tooth extraction socket is located in the anterior and posterior areas of the upper and lower jaws.
The area of the extraction socket (bone defect) in the mouth will need to be treated with artificial dental implants in the future.
The patient does not have systemic diseases (such as patients with hypertension, osteoporosis, bone-related diseases, kidney disease, thyroid and parathyroid diseases, etc.).

Exclusion Criteria4

Patients with potentially weakened healing abilities such as cancer, diabetes, bone infection, tuberculosis, anemia due to heme abnormalities or congenital immune deficiency, cellulitis, acute periodontal cyst, severe cusp disease (cyst size) \>2mm2) or patients with dental and jaw lesions.
Women who are pregnant or breastfeeding.
Exclude heavy smokers or betel nut chewers who smoke more than one pack of cigarettes per day.
The bone defect in the extraction socket is severe and requires other bone regeneration surgeries (GBR), otherwise it will not be possible to have enough volume to provide artificial dental implants in the future.

Print for Your Doctor

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDUREAutologous Tooth Root

An autologous Tooth Root is made from one's own tooth root and covered in an extraction socket where bone graft is placed.

DRUGVit.D3

Local administration of Vit.D3, through the effect of Vit.D3 to explore whether it can help to accelerate the healing of tooth extraction cavity and the clinical effectiveness of bone regeneration

OTHERbone graft

Selecting bone materials for alveolar ridge preservation according to treatment needs