RecruitingEarly Phase 1NCT07638358

Assessment of the Impact of Neobone® (Biphasic Calcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction

Assessment of Safety and Performance of Neobone®: A Prospective Observational Study in the Field of Dentistry

Sponsor

Egas Moniz - Cooperativa de Ensino Superior, CRL

Enrollment

30 participants

Start Date

Dec 1, 2025

Study Type

INTERVENTIONAL

Conditions

Tooth Extraction Site Healing Alveolar Ridge Preservation

Summary

The goal of this randomized clinical trial is to assess whether BCP (Biphasic Calcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction. The main question it aims to answer is whether using BCP for alveolar ridge preservation has a positive effect on bone volume compared with natural healing. The main questions it aims to answer are: Does BCP improve ridge preservation compared with natural healing? Researchers will compare BCP grafted sockets to natural healing sockets to see if BCP better preserves ridge volume. Participants will: Have a tooth indicated for extraction. Be assigned to either BCP or natural healing. Undergo CBCT (Cone Beam Computed Tomography) and intra-oral scanning after extraction and after six months of healing to measure horizontal and vertical resorption and bone density.

Eligibility

Min Age: 18 Years

Inclusion Criteria3

years or older
Acceptance of informed consent
Type 1 or 2 extraction sockets (Elian et al. 2007)

Exclusion Criteria7

Presence of active infection or severe inflammation in the intervention zone
Relevant medical history that contraindicates implant surgery
Patients with poor oral hygiene (full-mouth plaque score and full-mouth bleeding score >15%) and lack of motivation
Uncontrolled diabetes (reported levels of glycated haemoglobin exceeding 7%)
Uncontrolled and /or untreated periodontal disease
Heavy smokers (more than 10 cigarettes per day)
Immunosuppression