Tracking of Red Blood Cells Using Super Resolution Ultrasound in Persons With Healthy or Overuse Injured Tendons
SUper-Resolution Ultrasound Imaging of Erythrocytes (SURE) in Normal and Tendinopathic Tendons
University Hospital Bispebjerg and Frederiksberg
135 participants
Feb 8, 2024
OBSERVATIONAL
Conditions
Summary
The goal of this observational study is to test whether a new ultrasound method, called SUper Resolution ultrasound imaging of Erythrocytes (SURE), can image the small blood vessels found in tendons of persons with a tendon overuse injury (tendinopathy). The main questions it aims to answer are: * Is the method sensitive enough to detect the smallest blood vessels * What information about the blood flow can be obtained (flow velocity, pressure, shape of the vessels) * Can the flow in an injured tendon be distinguished from that of a healthy one Participants will receive a non-invasive ultrasound examination of their Achilles (heel) or patellar (knee) tendon, using an advanced high frequency research ultrasound system. Researchers will compare participants with either an Achilles or patellar tendon overuse injury to participants with healthy tendons, to see if there are distinct differences in the blood vessels that could help diagnose and treat the injuries.
Eligibility
Inclusion Criteria4
- to 70 years of age.
- BMI below 30.
- Able to lie still for 1 minute.
- Capable of providing signed informed consent.
Exclusion Criteria7
- Pregnancy.
- Dementia.
- Smoking.
- Diabetes.
- Arthritis.
- Current or historical injuries to the tendon or surrounding tissue aside from tendinopathy.
- Medical or surgical treatments for their tendinopathy that may influence blood flow.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Research ultrasound sequence for tracking erythrocytes and thereby generating a super-resolution image of the vasculature.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06142747