RecruitingNCT06142747

Tracking of Red Blood Cells Using Super Resolution Ultrasound in Persons With Healthy or Overuse Injured Tendons

SUper-Resolution Ultrasound Imaging of Erythrocytes (SURE) in Normal and Tendinopathic Tendons


Sponsor

University Hospital Bispebjerg and Frederiksberg

Enrollment

135 participants

Start Date

Feb 8, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to test whether a new ultrasound method, called SUper Resolution ultrasound imaging of Erythrocytes (SURE), can image the small blood vessels found in tendons of persons with a tendon overuse injury (tendinopathy). The main questions it aims to answer are: * Is the method sensitive enough to detect the smallest blood vessels * What information about the blood flow can be obtained (flow velocity, pressure, shape of the vessels) * Can the flow in an injured tendon be distinguished from that of a healthy one Participants will receive a non-invasive ultrasound examination of their Achilles (heel) or patellar (knee) tendon, using an advanced high frequency research ultrasound system. Researchers will compare participants with either an Achilles or patellar tendon overuse injury to participants with healthy tendons, to see if there are distinct differences in the blood vessels that could help diagnose and treat the injuries.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria4

  • to 70 years of age.
  • BMI below 30.
  • Able to lie still for 1 minute.
  • Capable of providing signed informed consent.

Exclusion Criteria7

  • Pregnancy.
  • Dementia.
  • Smoking.
  • Diabetes.
  • Arthritis.
  • Current or historical injuries to the tendon or surrounding tissue aside from tendinopathy.
  • Medical or surgical treatments for their tendinopathy that may influence blood flow.

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Interventions

DIAGNOSTIC_TESTSuper-Resolution Ultrasound Imaging of Erythrocytes (SURE)

Research ultrasound sequence for tracking erythrocytes and thereby generating a super-resolution image of the vasculature.


Locations(1)

Institute of Sports Medicine

Copenhagen, Denmark

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NCT06142747


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