A Study of LY3971297 in Healthy Participants

This is a Phase 1 study testing a new investigational drug called LY3971297 in healthy adult volunteers to assess its safety, tolerability, and how the body processes it. Some parts of the study focus on specific populations, such as people with obesity, kidney impairment, or specific ethnic backgrounds. **You may be eligible if...** - You are a generally healthy adult (for most study parts) - Your BMI is in the normal to overweight range (18.5–35), or the obese range (27–40) for specific parts - You have stable medical conditions (for the part testing people with obesity) - You may qualify for a kidney-impairment group if your kidney function is reduced and you are on stable medications **You may NOT be eligible if...** - You have significant heart, lung, liver, kidney, or neurological disease (for healthy volunteer parts) - You have a known or active psychiatric disorder - You have low blood pressure (systolic below 100 mmHg) or dizziness upon standing - You smoke more than 10 cigarettes per day - You have donated a large amount of blood recently - You drink more than the recommended daily amount of alcohol - For certain parts: you have polycystic kidney disease, lupus nephritis, or are on dialysis Talk to your doctor to see if this trial is right for you.