RecruitingNot ApplicableNCT06152614

MIND Foods and Aerobic Training in Black Adults With HTN

MIND Foods and Aerobic Training in Black Adults With HTN: An ADRD Prevention Pilot RCT


Sponsor

Indiana University

Enrollment

128 participants

Start Date

Nov 28, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this randomized controlled trial is to determine the impact of Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) diet and aerobic training on cognition in Black adults with high systolic blood pressure. Researchers will compare Food Delivery and Cooking PLUS Aerobic Training (FoRKS+) versus Enhanced Usual Care (EUC) to evaluate the effects on cognition. Participants will complete cognitive and cardiovascular assessments, 24-hr blood pressure monitoring, standard blood pressure measurements, weight, fingerstick for HbA1c point-of-care testing, and questionnaires. Participants may also choose to participate in an optional blood draw for DNA Repair Capacity testing as a modifiable risk factor for aging-associated diseases.


Eligibility

Min Age: 35 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a combination of the MIND diet (a brain-healthy eating pattern) and aerobic exercise can lower blood pressure and improve brain health in Black adults with high blood pressure. The study is specifically focused on Black adults, who are disproportionately affected by hypertension and related brain health complications. **You may be eligible if...** - You are 35–75 years old - You identify as non-Hispanic Black/African American - You live in Marion County - You have had a systolic blood pressure reading ≥ 140 mmHg in the past 12 months - You are physically inactive (less than 20 minutes of moderate exercise per day) - You have access to a kitchen at home and can cook - You have normal or near-normal cognition and are functionally independent **You may NOT be eligible if...** - You live in a nursing home or have dementia, Alzheimer's disease, mild cognitive impairment, Parkinson's disease, or a brain tumor/infection - You currently undergo chemotherapy or radiation - You have psychosis, schizophrenia, or bipolar disorder - You have hypertensive heart disease or hypertensive chronic kidney disease - You drink heavily (more than 8 drinks/week for women, 15/week for men) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALEnhanced Usual Care (EUC)

Enhanced Usual Care (EUC) includes 5 weeks of hypertension classes.

BEHAVIORALFood Delivery and Cooking PLUS Aerobic Training (FoRKS+)

Food Delivery and Cooking PLUS Aerobic Training (FoRKS+) includes 5 weeks of hypertension classes followed by 11 weeks of home-delivered Mediterranean-style ingredient kits and virtual cooking classes, and an additional 12 weeks of aerobic exercise.


Locations(1)

Eskenazi Health

Indianapolis, Indiana, United States

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NCT06152614


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