Cell Therapy and Myocardial Recovery in Heart Failure Patients Undergoing Left Ventricular Assist Device Support

This trial is studying whether cell therapy — using a patient's own stem cells — alongside implantation of a mechanical heart pump (Left Ventricular Assist Device, or LVAD) can help the heart muscle recover and potentially avoid the need for a heart transplant in people with non-ischemic dilated cardiomyopathy (a weakened heart not caused by blocked arteries). **You may be eligible if...** - You are 18–65 years old - You have been diagnosed with non-ischemic dilated cardiomyopathy (a weakened heart not caused by blocked arteries) - Your doctor has accepted you for an LVAD (mechanical heart support device) - You have been on optimal heart failure therapy for at least 2 months - You are able to give informed consent **You may NOT be eligible if...** - Your heart failure is caused by coronary artery disease (ischemic) - Your heart failure has a reversible untreated cause (such as thyroid disease or alcohol abuse) - You have a neuromuscular condition such as Duchenne muscular dystrophy - You have a recent or active infection, acute organ failure, severe anemia, or significant blood, liver, or kidney problems - You have a history of blood clots or bleeding disorders - You are significantly obese (BMI above 35) Talk to your doctor to see if this trial is right for you.