Organoids Based Drug Sensitivity in Neoadjuvant Chemotherapy of Breast Cancer

This study looks at whether testing cancer tissue in the lab (by growing mini-tumors called organoids) can help doctors predict which chemotherapy drugs will work best for breast cancer patients before surgery. The goal is to personalize treatment so patients get chemo that's more likely to shrink their tumor. **You may be eligible if...** - You are a woman between 18 and 70 years old - You have been diagnosed with early-stage breast cancer (stages I to IIIA) with a tumor at least 2 cm in size - Your cancer has not spread to distant parts of the body - You have not received any prior cancer treatment - Your overall health is good (able to carry out daily activities) - Your liver and kidney function are within acceptable limits **You may NOT be eligible if...** - You have already received treatment for breast cancer - You have inflammatory breast cancer or cancer that cannot be surgically removed - You have cancer in both breasts or in multiple areas of one breast - You are not a suitable candidate for chemotherapy before surgery Talk to your doctor to see if this trial is right for you.