RecruitingNot ApplicableNCT06164769

Enucleation of Pancreatic Tumor by Blocking Abdominal Trunk and Superior Mesenteric Artery

A Prospective Study of Enucleation of Pancreatic Tumor by Blocking Abdominal Trunk and Superior Mesenteric Artery


Sponsor

Zhejiang University

Enrollment

30 participants

Start Date

Mar 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Pancreatic enucleation could preserve more healthy pancreatic tissues and functions with a low recurrence risk. However, conventional enucleation can cause significant intraoperative bleeding, especially in which tumors in the pancreatic head, neck, and uncinate process of pancreas, as these tissues are rich in blood supply, mainly including the abdominal trunk and the superior mesenteric artery. In this study, we developed a novel method to control the pancreatic blood flow in laparoscopic enucleation--blocking the abdominal trunk and superior mesenteric artery with vascular occlusion clips in the process of resection, and evaluated its effectiveness and safety.


Eligibility

Min Age: 14 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study tests a surgical technique for removing small pancreatic tumors (enucleation) that uses a nerve block to temporarily reduce blood flow to the pancreas. This allows surgeons to remove the tumor more precisely while minimizing bleeding and preserving as much healthy pancreas tissue as possible. **You may be eligible if...** - You are an adult with a small pancreatic tumor suitable for enucleation (tumor removal without removing a large portion of the pancreas) - You are healthy enough to undergo abdominal surgery **You may NOT be eligible if...** - Your tumor is too large or positioned in a way that makes enucleation unsafe - You have conditions that make blocking the abdominal blood supply risky - You are pregnant - You have severe clotting or vascular disorders Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREblocking both the abdominal trunk and superior mesenteric artery in the pancreatic enucleation

In the pancreatic enucleation, Kocher Maneuver was routinely performed at first. Then free the left side of the abdominal trunk and superior mesenteric artery, loose tissues easy to free.After Kocher Maneuver and other surgical procedures, the abdominal trunk and superior mesenteric artery exposed. Before resection of pancreatic tumors, a vascular occlusion clamp clip was used to block the root of both the abdominal trunk and superior mesenteric artery to control the pancreatic blood flow.


Locations(1)

the Second Affiliated Hospital of Zhejiang University

Hangzhou, Zhejiang, China

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NCT06164769


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