RecruitingNot ApplicableNCT06166329

Interest of the Chair Lift Test in the Prognostic Evaluation of Pulmonary Embolism: a Single-center Open Prospective Study

Sponsor

University Hospital, Rouen

Enrollment

180 participants

Start Date

Feb 9, 2024

Study Type

INTERVENTIONAL

Conditions

Pulmonary Embolism Pulmonary Embolism Acute Non-severe Pulmonary Embolism Non-high-risk Pulmonary Embolism Prognostic Stratification Risk Assessment in Pulmonary Embolism Functional Exercise Testing Early Prognostic Evaluation

Summary

The objective of the study is to evaluate the prognostic performance of the chair lift test in the initial assessment of the severity of non-severe pulmonary embolism in hospitalized patients, in comparison with the current pulmonary embolism risk stratification score using the sPESI score refined by the use of cardiac biomarkers and right ventricular dysfunction

Eligibility

Min Age: 18 Years

Inclusion Criteria5

Diagnosis of pulmonary embolism according to clinical algorithm, confirmed by thoracic angioscan or ventilation perfusion (V/P) scan,
Non-serious pulmonary embolism, not requiring intensive care (thrombectomy or fibrinolysis not considered).
sPESI score ≥ 1 \[or = 0 with elevated troponin or presence of markers of VD dysfunction, or = 0 with need for hospitalization due to comorbidities unrelated to PE (social isolation, comprehension disorders, intercurrent infection, chronic renal failure, advanced cancer...)
Patients with no contraindications to chair lift testing (no O2 at the time of testing).
Effective anticoagulation for at least 1 hour.

Exclusion Criteria5

sPESI score = 0 with outpatient referral.
Diagnostic confirmation of Pulmonia Embolism by thoracic angioscan or scintigraphy more than 24h after suspicion of diagnosis.
Hospitalization \> 24h after introduction of anticoagulation, with subsequent confirmation by scintigraphy.
Any sign of serious Pulmonia Embolism, requiring hospitalization in an intensive care unit.
Asymptomatic Pulmonia Embolism discovered by chance

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