RecruitingNot ApplicableNCT06168669

A Safety and Effectiveness Prospective Blinded Clinical Study to Validate xBar System as Monitoring Tool for Anastomotic Leaks Detection


Sponsor

Exero Medical Ltd.

Enrollment

190 participants

Start Date

Mar 11, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Purpose: To validate the safety and effectiveness of xBar monitoring tool for detection of post-operative anastomotic leaks in subjects undergoing rectal/sigmoid resections with anastomosis. The clinical team is blinded to the leak detection of the xBar system.


Eligibility

Min Age: 22 Years

Inclusion Criteria5

  • Age ≥ 22 years
  • Indication for sigmoid or rectal resection surgery.
  • Usage of drain during the surgery (to be confirmed during the surgery)
  • Willing and able to comply with the study follow up.
  • Able and agree to provide an informed consent.

Exclusion Criteria7

  • Contraindication for surgery and/or general anesthesia.
  • Pregnancy or lactation.
  • Planned or unplanned fecal diversion during the surgery (to be confirmed during the surgery)
  • Known electronic device implanted in the chest or the abdominal cavity (e.g., pacemaker, cardioverter/defibrillator).
  • Major medical or psychiatric illness or condition, or other factors that may affect general health or ability to adhere to the follow-up schedule.
  • Known allergic reactions to materials used in the components of the xBar system, i.e., silicone, rubber and stainless-steel.
  • Participation in another interventional study during the xBar system usage.

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Interventions

DIAGNOSTIC_TESTxBar system

xBar system is surgical drain with embedded sensors. Collected data will be evaluated for an ability to identify anastomotic leaks. The xBar system does not have therapeutic indication.


Locations(13)

AdventHealth Orlando

Orlando, Florida, United States

AdventHealth Tampa

Tampa, Florida, United States

University of Louisville

Louisville, Kentucky, United States

Henry Ford Health

Detroit, Michigan, United States

Bryan Medical Center

Lincoln, Nebraska, United States

Weill Cornell MC, NY

New York, New York, United States

Mount Sinai Health System

New York, New York, United States

Northwell Health, NY

New York, New York, United States

Stony Brook University Hospital and Cancer Center

New York, New York, United States

HCA

Houston, Texas, United States

Soroka MC

Beersheba, Israel

Rabin MC

Petah Tikva, Israel

Kaplan MC

Rehovot, Israel

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NCT06168669


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