Anastomotic Leak Clinical Trials

15 recruiting

Anastomotic Leak Trials at a Glance

21 actively recruiting trials for anastomotic leak are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in New York, Tampa, and Amsterdam. Lead sponsors running anastomotic leak studies include Aesculap AG, Khyber Teaching Hospital, and Amsterdam UMC, location VUmc.

Browse anastomotic leak trials by phase

Treatments under study

About Anastomotic Leak Clinical Trials

Looking for clinical trials for Anastomotic Leak? There are currently 15 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Anastomotic Leak trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Anastomotic Leak clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 21 trials

Recruiting
Not Applicable

Endo-SPONGE for Treatment of Anastomotic or Hartmann's Stump Leakages in Lower Pelvic Area

Anastomotic LeaksHartmanns Stump Leakage
Boston Scientific Corporation66 enrolled6 locationsNCT07035431
Recruiting
Not Applicable

Stapler Reinforcement Patches Compared to Standard Staplers in Gastrojejunostomy

Gastric CancerPostoperative ComplicationsGastrostomy+1 more
Nanchong Central Hospital382 enrolled1 locationNCT06464978
Recruiting

Leakage Rate of Ileo-COlic Sutured Anastomosis After Right Hemicolectomy

Colon CancerAnastomotic LeakRight Hemicolectomy
Aesculap AG249 enrolled3 locationsNCT07132970
Recruiting
Not Applicable

Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections

Postoperative ComplicationsAnastomotic LeaksAnastomotic Complication+8 more
Medtronic - MITG137 enrolled8 locationsNCT07351071
Recruiting
Not Applicable

CRP Point-of-care Testing Trajectory, a Predictive Factor for Anastomotic Leak in Elective Colorectal Surgery

Colorectal SurgeryAnastomotic LeakEnhanced Recovery+2 more
Centre Hospitalier Universitaire, Amiens500 enrolled1 locationNCT07464600
Recruiting

Registry Study of People Who Are Having an Esophagectomy and Are at High Risk of Anastomotic Leak

Anastomotic LeakEsophageal Malignant Neoplasm Primary
Memorial Sloan Kettering Cancer Center40 enrolled7 locationsNCT07449208
Recruiting

Impact of Endo-vac Therapy for Esophago-jejunal Anastomotic Leak

Esophagojejunal Anastomotic Leak
Ukrainian Society of Clinical Oncology100 enrolled1 locationNCT07295236
Recruiting
Not Applicable

Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer

Quality of LifeRectal NeoplasmsLow Anterior Resection Syndrome+1 more
Sixth Affiliated Hospital, Sun Yat-sen University256 enrolled1 locationNCT05943444
Recruiting

Endoluminal Vacuum Therapy to Prevent Anastomotic Leakage After Esophagectomy Due to Esophageal Cancer

Esophageal CancerEsophagus CancerAnastomotic Leak
Aesculap AG44 enrolled1 locationNCT06097078
Recruiting
Not Applicable

A Safety and Effectiveness Prospective Blinded Clinical Study to Validate xBar System as Monitoring Tool for Anastomotic Leaks Detection

Colorectal SurgeryAnastomotic Leak
Exero Medical Ltd.190 enrolled13 locationsNCT06168669
Recruiting

Anastomotic Leakage After Colorectal Surgery.

Anastomotic Leak
Minia University430 enrolled1 locationNCT07144683
Recruiting
Not Applicable

Outcomes of a Single Chest Drain vs Two Drains

Esophageal AdenocarcinomaPleura; EffusionEsophageal Anastomotic Leak
Khyber Teaching Hospital68 enrolled1 locationNCT07125248
Recruiting

Role of Indexed Oxygen Delivery in Anastomotic Insufficiencies in Elective Laparoscopic Colorectal Resections for Cancer

Anastomosis; ComplicationsAnastomosis, SurgicalAnastomosis, Leaking+8 more
Saint Camillus International University of Health Sciences100 enrolled1 locationNCT07099820
Recruiting
Not Applicable

PARLAR-02 Trial:Modified Transanal Drainage Tube Use for Preventing Anastomotic Leakage

Anastomotic Leak
Third Military Medical University968 enrolled1 locationNCT07036588
Recruiting
Not Applicable

Resumption of Enteral Feeding After Bowel Anastomosis

Enhanced Recovery After SurgeryAnastomotic LeakFlatus+3 more
Khyber Teaching Hospital204 enrolled1 locationNCT06906289
Recruiting
Not Applicable

Evaluation of Colonic Perfusion by Indocyanine Green Angiography During Colorectal Surgery

Anastomotic Leak
University of Roma La Sapienza562 enrolled1 locationNCT06793280
Recruiting

Anastomotic Leakage After Right Hemicolectomy for Cancer, a Prospective Multicenter Study of SICO-CC Network

Anastomotic Leak Large IntestineRight Colon Tumors
San Luigi Gonzaga Hospital1,839 enrolled1 locationNCT06688383
Recruiting

Anastomotic Leakage in Right Colectomy

Anastomotic Leak
Barmherzige Brüder Vienna3,446 enrolled1 locationNCT06553261
Recruiting

Endoscopic Vacuum Therapy for Transmural Defects in the Upper Gastrointestinal Tract

Anastomotic LeakEndoscopic Vacuum TherapyEsophageal Perforation+3 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)200 enrolled1 locationNCT05606822
Recruiting

Routine Endoscopic Evaluation of Colorectal Anastomoses for Early Detection of Anastomotic Leakage

Anastomotic Leak Rectum
Amsterdam UMC, location VUmc150 enrolled5 locationsNCT06493565