RecruitingPhase 1NCT06171607

Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses

Characterizing Breast Masses Using an Integrative Framework of Machine Learning and Radiomics


Sponsor

University of Southern California

Enrollment

100 participants

Start Date

Nov 5, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

This clinical trial investigates the role of contrast enhanced ultrasound (CEUS) in identifying cystic breast masses as benign or malignant. Ultrasound is a diagnostic imaging test that uses sound waves to make pictures of the body without using radiation (x-rays). Ultrasounds are widely used to diagnose many diseases in the body. This trial may help researchers learn if using CEUS will help in determining whether or not an ultrasound guided biopsy is necessary.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing different imaging methods — including contrast-enhanced ultrasound (CEUS), which uses tiny gas bubbles to improve ultrasound images — against biopsy results to see how well these techniques can distinguish between cancerous and non-cancerous breast lumps. **You may be eligible if...** - You are a female 18 years or older - You have a newly found breast lump rated as suspicious (BIRADS 4a, 4b, 4c, or 5) on standard ultrasound - You have been recommended for an ultrasound-guided biopsy **You may NOT be eligible if...** - You have pulmonary hypertension or a known allergy to the ultrasound contrast agent - You are pregnant, possibly pregnant, or breastfeeding - You are currently receiving chemotherapy before surgery (neoadjuvant treatment) - Your breast lump is 1 cm or smaller - You have breast implants - The same breast has had prior cancer surgery (lumpectomy) - You have had a prior biopsy of that specific lump - You are under 30 years old (for certain imaging types) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDUREContrast-Enhanced Ultrasound

Undergo CEUS

DRUGPerflutren Lipid Microspheres

Given IV

DRUGSulfur Hexafluoride Lipid Microspheres

Given IV


Locations(2)

Los Angeles County-USC Medical Center

Los Angeles, California, United States

USC / Norris Comprehensive Cancer Center

Los Angeles, California, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06171607


Related Trials