RecruitingPhase 1Phase 2NCT06173999

A Study of SHR2554 With Chemotherapy in Treatment-naïve Patients With Peripheral T-cell Lymphoma

A Phase Ib/II, Open-label, Multi-center Study of SHR2554 With CHOP/CHOEP in Treatment-naïve Patients With Peripheral T-cell Lymphoma


Sponsor

Jiangsu HengRui Medicine Co., Ltd.

Enrollment

100 participants

Start Date

Dec 22, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The study is being conducted to evaluate the safety and efficacy of SHR2554 with CHOP/CHOEP in treatment- naïve peripheral T-cell lymphoma.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing a new drug called SHR2554 combined with chemotherapy as a first treatment for people who have just been diagnosed with peripheral T-cell lymphoma — a group of blood cancers that start in T cells, a type of immune cell. **You may be eligible if...** - You are between 18 and 70 years old - You have been newly diagnosed with peripheral T-cell lymphoma (confirmed by biopsy) - You have not yet received any chemotherapy or treatment for this lymphoma - You are in reasonably good health (ECOG performance status 0-1) with a life expectancy of at least 12 weeks - You have at least one measurable tumor on imaging **You may NOT be eligible if...** - You have active hepatitis B or hepatitis C infection - You have a history of significant heart disease - You have had another cancer in the past 5 years - You are pregnant or breastfeeding - You had major surgery in the past 4 weeks Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSHR2554/CHOP

SHR2554 with CHOP

DRUGSHR2554/CHOEP

SHR2554 with CHOEP


Locations(1)

Beijing Cancer Hospital

Beijing, Beijing Municipality, China

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NCT06173999


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