RecruitingNot ApplicableNCT06182059

Persistent Post Surgical Pain After Total Knee Arthroplasty

Enhanced Recovery After Surgery and Total Knee Replacement: A Prospective, Randomized Study on the Rule of Peripheral Nerve Blocks on Persistent Postoperative Pain Six Months After Surgery


Sponsor

Policlinico di Monza SpA

Enrollment

436 participants

Start Date

Jan 12, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Patients undergone total knee replacement are randomized to receive a "fast track" regional anesthesia protocol or a "traditional" regional anesthesia continuous infusion by both a femoral and sciatic catheter to assess if this latter technique may reduce persistent postoperative pain six months after surgery


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria1

  • primary total knee replacement with a written informed consent

Exclusion Criteria4

  • Allergy to local anesthetics or any drugs involve in the study
  • Controindication to regional anesthesia
  • chronic use of opioids
  • BMI > 35 kg m2

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Interventions

PROCEDUREcontinuous peripheral nerve block

continuous regional anesthesia in total knee replacement


Locations(1)

Policlinico di Monza SPA

Monza, Monza Brianza, Italy

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NCT06182059


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