RecruitingNot ApplicableNCT06184152

CEUS vs. AMRI for HCC Detection in Patients With Indeterminate Liver Nodules

Contrast Ultrasound vs. Abbreviated MRI for Detection of HCC in Patients With Indeterminate Liver Nodules


Sponsor

University of Texas Southwestern Medical Center

Enrollment

600 participants

Start Date

Nov 28, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The study will be conducted at the following locations: 1. UT Southwestern Medical Center 2. Parkland Health and Hospital System 3. University of Michigan Investigators will prospectively compare the performance of dynamic contrast enhanced abbreviated MRI (AMRI) and contrast-enhanced ultrasound for early-stage HCC detection in patients with indeterminate liver nodules.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study compares two imaging methods — contrast-enhanced ultrasound (CEUS) and a specialized MRI scan — to see which is better at detecting liver cancer (hepatocellular carcinoma, or HCC) in people with cirrhosis who have small liver spots that haven't been confirmed as cancer yet. **You may be eligible if...** - You are 18 years or older - You have cirrhosis of the liver from any cause (such as hepatitis or alcohol use) - A recent CT or MRI scan found at least one small, unclear spot on your liver - You have not been diagnosed with liver cancer yet **You may NOT be eligible if...** - You have had a liver transplant - You currently have another type of cancer at the same time - You have a known allergy to contrast dye used in imaging - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTCEUS imaging

Contrast-enhanced ultrasound (CEUS)

DIAGNOSTIC_TESTaMRI imaging

contrast enhanced abbreviated MRI (AMRI)


Locations(2)

University of Michigan

Ann Arbor, Michigan, United States

University of Texas Southwestern Medical Center

Dallas, Texas, United States

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NCT06184152


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