RecruitingNot ApplicableNCT06184646

Elucidating the Minimal Effective Dose of Prunes for Bone Health in Postmenopausal Women

Effect of Calcium and Vitamin D Supplements and/or Prunes on Bone Health


Sponsor

San Diego State University

Enrollment

200 participants

Start Date

Mar 15, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of this study is to examine if calcium and vitamin D supplements and/or prune can prevent bone loss in postmenopausal women.


Eligibility

Sex: FEMALE

Inclusion Criteria3

  • Postmenopausal
  • BMD t-score is between 0.5 and 2 SD below the mean
  • Not on hormone replacement therapy (HRT) and/or other pharmacological agents known to affect bone for at least three months prior to initiation of the study

Exclusion Criteria4

  • Women whose BMD t-score at any site falls below 2.5 SD of the mean
  • Subjects receiving endocrine (e.g., prednisone, other glucocorticoids) or neuroactive (e.g., dilantin, phenobarbital) drugs or any drugs known to influence bone and calcium metabolism
  • Subjects who smoke cigarettes or vape
  • Regular consumption of dried plum or prune juice

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Interventions

DIETARY_SUPPLEMENTPrune

30 g of prune/day


Locations(1)

San Diego State University

San Diego, California, United States

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NCT06184646


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