RecruitingPhase 2NCT06190639

A Clinical Study of Sintilimab as Adjuvant Therapy in Node-positive ESCC

A Clinical Study of Sintilimab as Adjuvant Therapy in Node-positive Esophageal Squamous Cell Carcinoma After Radical Surgery Without Neoadjuvant Therapy


Sponsor

Zhejiang Cancer Hospital

Enrollment

31 participants

Start Date

Oct 25, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to evaluate the efficacy and safety of sintilimab as adjuvant therapy in node-positive esophageal squamous cell carcinoma after radical surgery without neoadjuvant therapy. The main question it aims to answer is: • Efficacy of sintilimab as adjuvant therapy Participants will receive sintilimab 200 mg once on day 1, every 21 days(Q3W).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing sintilimab (an immunotherapy drug) as a treatment taken after surgery for esophageal squamous cell cancer that had spread to nearby lymph nodes, to see if it helps prevent the cancer from coming back. **You may be eligible if...** - You are 18 or older - You have been diagnosed with thoracic esophageal squamous cell cancer with lymph node involvement (stage T1–T3 N+ M0) - You have had complete surgical removal of your esophageal cancer within the past 4–12 weeks - You are confirmed cancer-free by scans taken after surgery - Your general health is good (ECOG 0–1) and your blood counts and organ function meet study thresholds **You may NOT be eligible if...** - You have any remaining cancer after surgery - You are pregnant or breastfeeding - Your organ function (kidneys, liver) does not meet the required levels Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGsintilimab

200 mg once on day 1, every 21 days


Locations(1)

Zhejiang Cancer Hospital

Hangzhou, Zhejiang, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06190639


Related Trials