DEB-TACE With Visualable Microspheres Versus PVA Microspheres for HCC

This study is comparing two types of tiny beads used during a liver artery procedure (called TACE) to treat liver cancer — one type is visible on imaging (DEB with visualable microspheres) versus standard beads — to see which works better. **You may be eligible if...** - You have liver cancer (hepatocellular carcinoma) that requires the TACE procedure - You are not a candidate for surgery, liver transplant, or ablation, or you have declined those options - Your liver function is classified as Child-Pugh A or B (reasonably preserved) - Your general health score (ECOG) is 0–2 - You have at least one measurable tumor that has not yet been treated with TACE **You may NOT be eligible if...** - Your liver cancer has spread outside the liver - Your liver function is severely impaired (Child-Pugh C) - Your kidney function is severely impaired - You have a complete blockage of the main portal vein by tumor Talk to your doctor to see if this trial is right for you.