Overtaking Intra and Inter Tumoral Heterogeneity In Von Hippel-Lindau Related Renal Cancer

This study looks at how kidney tumors in people with Von Hippel-Lindau (VHL) syndrome differ from one another — both within a single tumor and between different tumors in the same person. VHL is a rare inherited condition that causes tumors to grow in the kidneys and other organs. **You may be eligible if...** - You have been diagnosed with VHL syndrome - You have at least 3 kidney tumors larger than 3 cm that need to be surgically removed **You may NOT be eligible if...** - You do not have VHL syndrome - You have fewer than 3 kidney tumors - You are not scheduled for kidney surgery Talk to your doctor to see if this trial is right for you.