RecruitingNCT06196307

Early Warning and Classification Model for Acute Non-traumatic Chest Pain

A Prospective Study of Acute Nontraumatic Chest Pain - Warning and Classification


Sponsor

Xiao-nan He

Enrollment

10,000 participants

Start Date

Aug 30, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Acute non-traumatic chest pain is one of the common causes of presentation in emergency patients, but the causes of acute non-traumatic chest pain are complex, the severity of the condition varies greatly, and the specificity of symptoms is not high. Machine learning and intelligent auxiliary models can greatly shorten the time of clinical decision-making, and improve the accuracy of etiological diagnosis in patients with chest pain, reduce the rate of misdiagnosis and missed diagnosis, and provide a clear direction for further treatment.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Age ≥ 18 years
  • Symptom onset or worsening within 24 hours before presentation, with a chief complaint of acute chest pain meeting the broad definition of chest pain (2021 AHA)
  • Presentation to the emergency department, with a clinical diagnosis consistent with non-traumatic chest pain
  • Signed informed consent

Exclusion Criteria3

  • traumatic chest pain
  • systemic pain caused by malignant tumors or rheumatic diseases involving the chest
  • Patients were lost to follow-up

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Interventions

COMBINATION_PRODUCTClinical evaluation, laboratory and cardiac imaging results, medication, surgery, and any hospitalization

Examination: Electrocardiogram、 imaging examination、 X-ray, CTA, bedside echocardiography. Laboratory test results of patients, including complete blood count, D-dimer, myocardial injury markers, sST2, MPO, and other indicators. History of cardiovascular and pulmonary vascular drug therapy: Antithrombotic therapy (type, measurement) , Anticoagulation therapy (type, metering), Other drug treatments (type, measurement)


Locations(1)

Xiaonan He

Beijing, Chaoyang, China

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NCT06196307


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