RecruitingNot ApplicableNCT07435168

CHEST-CA: Study of Chest Pain and Hidden Cardiac Amyloidosis


Sponsor

Rigshospitalet, Denmark

Enrollment

300 participants

Start Date

Apr 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of this observational, prospective study is to determine the prevalence of Cardiac Amyloidosis (CA) in males over the age of 65 who experience chest pain but show no signs of coronary artery disease (CAD). Prior to inclusion, all patients will have undergone a CT coronary angiogram or an Rb-PET scan to rule out the possibility of CAD. Participants will be subject to several examinations, including blood tests, urine samples, ECG, echocardiography, and bone scintigraphy. An endomyocardial biopsy may be conducted if necessary.


Eligibility

Sex: MALEMin Age: 65 Years

Inclusion Criteria1

  • No signs of CAD through Rb-PET and/or CT coronary arteriogram

Exclusion Criteria1

  • Previous history of amyloidosis

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Interventions

OTHERScreening thourgh examinations including bonescintigraphy

Clinical examination, blood samples, echo, bone scintigraphy


Locations(1)

Rigshospitalet

Copenhagen, Denmark

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NCT07435168


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