RecruitingNCT06197984

Antimicrobial Resistance in Acute Cholangitis

Exploring Antimicrobial Resistance in Patients With Acute Cholangitis Undergoing ERCP: A Prospective Multicentre Study


Sponsor

Emergency County Hospital Pius Brinzeu; Timisoara, Romania

Enrollment

1,700 participants

Start Date

Jan 8, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This study prospectively explores antimicrobial resistance in patients with acute cholangitis undergoing ERCP procedures. By analyzing patient profiles, microbial cultures, and treatment outcomes, the current study seeks to identify specific patterns of resistance, assess the effectiveness of current antimicrobial therapies, and explore potential strategies to optimize treatment regimens.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Patients with acute cholangitis
  • Ability to provide an informed consent
  • Age over 18 years
  • Any gender

Exclusion Criteria6

  • Age under 18
  • Pregnancy
  • Post-ERCP perforation
  • The patient's decision to abstain from study enrollment
  • Patients unable to express informed consent
  • Patients from whom a bile sample could not be collected.

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Interventions

PROCEDUREERCP

ERCP will serve as the exclusive therapeutic modality, aided by a therapeutic duodenoscope to access the common bile duct using a guidewire.


Locations(1)

Bogdan Miutescu

Timișoara, Romania

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NCT06197984


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