Comparative Efficacy Of Intraductal Antibiotic During ERCP In Acute Cholangitis
Comparative Efficacy Of Intraductal Antibiotic During ERCP In Acute Cholangitis: A Randomized Controlled Trial
National University of Malaysia
172 participants
Jul 9, 2024
INTERVENTIONAL
Conditions
Summary
Does intraductal administration of antibiotics during endoscopic retrograde cholangiopancreatography (ERCP), in addition to standard systemic antibiotic therapy, improve clinical outcomes in patients with acute cholangitis compared with standard systemic antibiotic therapy alone?
Eligibility
Inclusion Criteria3
- The patients diagnosed with mild and moderate acute cholangitis based on TG 18
- Planned for ERCP within 48 hours
- years old and above
Exclusion Criteria6
- Severe acute cholangitis
- History of antibiotic hypersensitivity
- Receiving cancer chemotherapy, steroids, or immunosuppressive agents
- Concomitant infections
- Recent biliary interventions such as percutaneous transhepatic biliary drainage (PTBD) within last 3 months
- Known or suspected perforated tympanic membrane, myasthenia gravis
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Administration described in arm/group description
Administration described in arm/group description
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07407491