RecruitingNot ApplicableNCT06202105

Comparison of Laparoscopic and Open Total Gastrectomy for Locally Advanced Gastric Cancer

Comparison of Laparoscopic Versus Open Total Gastrectomy for Locally Advanced Gastric Cancer: a Prospective Randomized Control Trial

Sponsor

University Medical Center Ho Chi Minh City (UMC)

Enrollment

210 participants

Start Date

Aug 2, 2024

Study Type

INTERVENTIONAL

Conditions

Gastric Cancer

Summary

Evidence of implementation of laparoscopic total gastrectomy (LTG) for locally advanced gastric cancer (GC) remains inadequate. This study aimed to compare short- and mid-term outcomes of LTG versus open total gastrectomy (OTG) for cT2-4a GC.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria6

Pathologic finding by gastric endoscopy: confirmed gastric adenocarcinoma
Age: 18 - 80 year old
Tumor required total gastrectomy for radical treatment
Preoperative cancer stage (CT scan stage): cT2-4aNanyM0
ASA score: ≤ 3
Informed consent patients (explanation about our clinical trials is provided to the patients or patrons, if patient is not available)

Exclusion Criteria4

Concurrent cancer or patient who was treated due to other cancer before the patient was diagnosed gastric cancer
Bulky lymph node andd/or Para-aortic lymph node metastasis
Combined esophagectomy due to invading to the esophagus
Pregnant patient