RecruitingNCT06205953

A EUropean REgistry and Sample Sharing networK to Promote the Diagnosis and Management of Light Chain Amyloidosis (EUREKA)

Bonding Molecular Genotyping and Phenotyping to Outcome Measures in AL Amyloidosis: A EUropean REgistry and Sample Sharing networK to Promote the Diagnosis and Management of Light Chain Amyloidosis (EUREKA)


Sponsor

Fondazione IRCCS Policlinico San Matteo di Pavia

Enrollment

400 participants

Start Date

Jan 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

A prospective patients' registry collecting all new cases of AL amyloidosis evaluated at referral Centers from across Europe and a sample sharing network will be created to study mechanisms of the disease through the use of advanced molecular technologies and big data analysis tools.


Eligibility

Min Age: 18 YearsMax Age: 99 Years

Inclusion Criteria5

  • diagnosis of systemic AL amyloidosis;
  • treatment-naïve;
  • age ≥18 years;
  • ability to understand and willingness to sign an informed consent;
  • planned follow-up at participating center.

Exclusion Criteria2

  • non-AL amyloidosis;
  • previous treatment for AL amyloidosis.

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Locations(6)

Medical Department, Amyloidosis Center, University Hospital, Im Neuenheimer Feld 672

Heidelberg, Germany

Fondazione IRCCS Policlinico San Matteo, Pavia, Viale Golgi 19, 27100

Pavia, Italy

UMC Utrecht, dept Hematology, Amyloid Expertise Center, Utrecht, Heidelberglaan

Utrecht, Netherlands

Instituto de Investigación Sanitaria de Navarra (IdiSNA) C. de Irunlarrea, 3, 31008 Pamplona, Navarra

Pamplona, Spain

University of Applied Sciences and Arts Northwestern Switzerland, Institute of Medical Engineering and Medical Informatics

Muttenz, Switzerland

Universidad de la Republica Hospital de Clinicas "Dr Manuel Quintela"

Montevideo, Uruguay

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NCT06205953


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