RecruitingNCT06206369

Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression

Sponsor

Amsterdam UMC, location VUmc

Enrollment

11,000 participants

Start Date

Oct 31, 2023

Study Type

OBSERVATIONAL

Conditions

Peripheral Arterial Disease Aneurysm Abdominal

Summary

The VASCULAID-RETRO study, within the broader VASCULAID project, aims to create artificial intelligence (AI) algorithms that can predict cardiovascular events and the progression of abdominal aortic aneurysm (AAA) and peripheral arterial disease (PAD). The study plans to gather and analyze data from at least 5000 AAA and 6000 PAD patients, combining existing cohorts and retrospectively collected data. During this project, AI tools will be developed to perform automatic anatomical segmentation and analyses on multimodal imaging. AI prediction algorithms will be developed based on multisource data (imaging, medical history, -omics).

Eligibility

Min Age: 40 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study builds AI-powered tools to better predict the risk and progression of aortic aneurysms (dangerous bulges in the main artery). Researchers will use imaging and health data from patients to train and test these tools. **You may be eligible if...** - You are between 40 and 90 years old - You have an aortic aneurysm larger than 3 cm (about 1.2 inches) - This includes various types: abdominal, near the kidneys, involving the iliac artery, or unusual types like mycotic aneurysms - Patients who have already had surgery or experienced a rupture may also be included **You may NOT be eligible if...** - You are outside the 40–90 age range - You do not have an aortic aneurysm meeting the size or type criteria Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.